Sadowsky, Jack: search on Z-Library

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1

Immolation of p-aminobenzyl ether linker and payload potency and stability determine the cell killing activity of antibody-drug conjugates with phenol-containing payloads

Zhang, Donglu, Le, Hoa, Cruz-Chuh, Josefa dela, Bobba, Sudheer, Guo, Jun, Staben, Leanna, Zhang, Chenghong, Ma, Yong, Kozak, Katherine Ruth, Lewis-Phillips, Gail D., Vollmar, Breanna, Sadowsky, Jack,

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 575 KB

english, 2018

2

Histologic and mammographic specificity of risk factors for benign breast disease

Roselie A. Bright, Alan S. Morrison, Jacques Brisson, Nelson A. Burstein, Norman L. Sadowsky, Daniel B. Kopans, Jack E. Meyer

Journal:

Year:

1989

Language:

english

File:

PDF, 490 KB

english, 1989

3

Development of a cysteine-conjugatable disulfide FRET probe: Influence of Charge on Linker Cleavage and Payload Trafficking for an anti-HER2 antibody conjugate

Scales, Suzie, Tsai, Siao Ping, Zacharias, Neelie, Cruz-Chuh, Josefa dela, Bullen, Gordy, Velasquez, Erick, Chang, Julie, Bruguera, Elise, Kozak, Katherine Ruth, Sadowsky, Jack

Journal:

Bioconjugate Chemistry

Year:

2019

Language:

english

File:

PDF, 1.61 MB

english, 2019

4

Modulating ADC payload metabolism by conjugation site and linker modification

Su, Dian, Kozak, Katherine, Sadowsky, Jack, Yu, Shang-Fan, Fourie-O’Donohue, Aimee, Nelson, Christopher, Vandlen, Richard, Ohri, Rachana, Liu, Luna, Ng, Carl, He, Jintang, Davis, Helen, Lau, Jeff, Del

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

5

Exploration of Backbone Space in Foldamers Containing α- and β-Amino Acid Residues: Developing Protease-Resistant Oligomers that Bind Tightly to the BH3-Recognition Cleft of Bcl-xL

Jack D. Sadowsky, Justin K. Murray, York Tomita, Samuel H. Gellman

Journal:

Year:

2007

Language:

english

File:

PDF, 1.22 MB

english, 2007

6

Cathepsin B is dispensable for cellular processing of cathepsin B-cleavable antibody-drug conjugates

Caculitan, Niña G., dela Cruz Chuh, Josefa, Ma, Yong, Zhang, Donglu, Kozak, Katherine R, Liu, Yichin, Pillow, Thomas H., Sadowsky, Jack, Cheung, Tommy K, Phung, Qui, Haley, Benjamin, Lee, Byoung-Chul,

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 2.91 MB

english, 2017

7

Central hemangioma of the mandible: Literature review, case report, and discussion

Donald Sadowsky, Ronald D. Rosenberg, Jack Kaufman, Barry C. Levine, Joel M. Friedman

Journal:

Oral Surgery, Oral Medicine, Oral Pathology

Year:

1981

Language:

english

File:

PDF, 2.23 MB

english, 1981

8

O2-03-05: Early detection of Alzheimer’s disease-linked aβ peptide accumulation in the lens by non-invasive quasi-elastic light scattering

Juliet Moncaster, Robert D. Moir, Ling Fu, Anca Mocofanescu, Suqian Lu, Weilan Xu, Oliver Chadwick, Jack T. Rogers, Martin Sadowski, Thomas Wisniewski, William E. Klunk, Chester A. Mathis, John I. Cla

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

9

Neuroendocrine Tumor of the Pancreas as a Unique Manifestation of Cowden Syndrome: a Case Report

Neychev, V, Sadowski, SM, Jack, Zhu, Allgaeuer, Michael, Kilian, K, Meltzer, P, Kebebew, E

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2015

Language:

english

File:

PDF, 2.13 MB

english, 2015

10

An Anti-CLL-1 Antibody-Drug Conjugate for the Treatment of Acute Myeloid Leukemia

Zheng, Bing, Yu, Shang-Fan, del Rosario, Geoffrey, Leong, Steven R, Lee, Genee Y, Vij, Rajesh, Chiu, Cecilia P.C., Liang, Wei-Ching, Wu, Yan, Chalouni, Cecile, Sadowsky, Jack, Clark, Vanessa M, Hendri

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.02 MB

english, 2018

11

Efficient Synthesis of a β-Peptide Combinatorial Library with Microwave Irradiation

Murray, Justin K., Farooqi, Bilal, Sadowsky, Jack D., Scalf, Mark, Freund, Wesley A., Smith, Lloyd M., Chen, Jiandong, Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 258 KB

english, 2005

12

Myotonic dystrophy: Surgical and anesthetic considerations during orthognathic surgery

Kaufman, Jack, Friedman, Joel M., Sadowsky, Donald, Harris, Joel

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

1983

Language:

english

File:

PDF, 745 KB

english, 1983

13

New Family of Biuret Hydrolases Involved in s -Triazine Ring Metabolism

Cameron, Stephan M., Durchschein, Katharina, Richman, Jack E., Sadowsky, Michael J., Wackett, Lawrence P.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

14

Putting Plasticity in Its Place

Sadowski, Josef H. L. P., Mellor, Jack R.

Journal:

Frontiers in Neuroscience

Year:

2012

Language:

english

File:

PDF, 216 KB

english, 2012

15

Breast Imaging

Kopans, Daniel B., Meyer, Jack E., Sadowsky, Norman

Journal:

Boston Medical and Surgical Journal

Year:

1984

Language:

english

File:

PDF, 5.15 MB

english, 1984

16

Ring-Closing Metathesis of Olefinic Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides

Blackwell, Helen E., Sadowsky, Jack D., Howard, Rebecca J., Sampson, Joshua N., Chao, Jeffery A., Steinmetz, Wayne E., O'Leary, Daniel J., Grubbs, Robert H.

Journal:

Journal of Organic Chemistry

Year:

2001

Language:

english

File:

PDF, 228 KB

english, 2001

17

(α/β+α)-Peptide Antagonists of BH3 Domain/Bcl-x L Recognition: Toward General Strategies for Foldamer-Based Inhibition of Protein−Protein Interactions

Sadowsky, Jack D., Fairlie, W. Douglas, Hadley, Erik B., Lee, Hee-Seung, Umezawa, Naoki, Nikolovska-Coleska, Zaneta, Wang, Shaomeng, Huang, David C. S., Tomita, York, Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

2007

Language:

english

File:

PDF, 737 KB

english, 2007

18

Modulating Therapeutic Activity and Toxicity of Pyrrolobenzodiazepine Antibody–Drug Conjugates with Self-Immolative Disulfide Linkers

Pillow, Thomas H., Schutten, Melissa, Yu, Shang-Fan, Ohri, Rachana, Sadowsky, Jack, Poon, Kirsten Achilles, Solis, Willy, Zhong, Fiona, Del Rosario, Geoffrey, Go, Mary Ann T., Lau, Jeffrey, Yee, Sharo

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 711 KB

english, 2017

19

Intratumoral Payload Concentration Correlates with the Activity of Antibody- Drug Conjugates

Zhang, Donglu, Yu, Shang-Fan, Khojasteh, S Cyrus, Ma, Yong, Pillow, Thomas H., Sadowsky, Jack D, Su, Dian, Kozak, Katherine R, Xu, Keyang, Polson, Andrew G, Dragovich, Peter, Hop, Cornelis ECA

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 2.05 MB

english, 2018

20

Convergent metabotropic signalling pathways inhibit SK channels to promote synaptic plasticity in the hippocampus

Tigaret, Cezar M., Chamberlain, Sophie E. L., Sadowski, Joseph H. L. P., Ashby, Michael C., Mellor, Jack R.

Journal:

Journal of Neuroscience

Year:

2018

Language:

english

File:

PDF, 4.67 MB

english, 2018

21

Chimeric (α/β + α)-Peptide Ligands for the BH3-Recognition Cleft of Bcl-x L : Critical Role of the Molecular Scaffold in Protein Surface Recognition

Sadowsky, Jack D., Schmitt, Margaret A., Lee, Hee-Seung, Umezawa, Naoki, Wang, Shaomeng, Tomita, York, Gellman, Samuel H.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

22

NMR studies on the solution structure of a deletion mutant of the transcarboxylase biotin carrier subunit

Matthias M. Jank, Jack D. Sadowsky, Claudia Peikert, Stefan Berger

Journal:

International Journal of Biological Macromolecules

Year:

2002

Language:

english

File:

PDF, 281 KB

english, 2002

23

High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL

Erinna F. Lee, Jack D. Sadowsky, Brian J. Smith, Peter E. Czabotar, Kimberly J. Peterson-Kaufman, Peter M. Colman, Samuel H. Gellman, W. Douglas Fairlie

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 962 KB

english, 2009

24

Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein–protein recognition: Application to the Bim BH3 domain

Melissa D. Boersma, Jack D. Sadowsky, York A. Tomita, Samuel H. Gellman

Journal:

Protein Science

Year:

2008

Language:

english

File:

PDF, 347 KB

english, 2008

25

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1

Rettenmaier, T. Justin, Sadowsky, Jack D., Thomsen, Nathan D., Chen, Steven C., Doak, Allison K., Arkin, Michelle R., Wells, James A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

26

Ripples Make Waves: Binding Structured Activity and Plasticity in Hippocampal Networks

Sadowski, Josef H. L. P., Jones, Matthew W., Mellor, Jack R.

Journal:

Neural Plasticity

Year:

2011

Language:

english

File:

PDF, 892 KB

english, 2011

27

Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates

Pillow, Thomas H., Sadowsky, Jack D., Zhang, Donglu, Yu, Shang-Fan, Del Rosario, Geoffrey, Xu, Keyang, He, Jintang, Bhakta, Sunil, Ohri, Rachana, Kozak, Katherine R., Ha, Edward, Junutula, Jagath R.,

Journal:

Chemical Science

Year:

2016

Language:

english

File:

PDF, 818 KB

english, 2016

28

Development of efficient chemistry to generate site-specific disulfide-linked protein- and peptide-payload conjugates: Application to THIOMAB™ antibody-drug conjugates

Sadowsky, Jack David, Pillow, Thomas H, Chen, Jinhua, Fan, Fang, He, Changrong, Wang, Yanli, Yan, Gang, Yao, Hui, Xu, Zijin, Martin, Shanique, Zhang, Donglu, Chu, Phillip, Cruz-Chuh, Josefa dela, O'Do

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 6.18 MB

english, 2017

29

Linker Immolation Determines Cell Killing Activity of Disulfide-Linked Pyrrolobenzodiazepine Antibody–Drug Conjugates

Zhang, Donglu, Pillow, Thomas H., Ma, Yong, Cruz-Chuh, Josefa dela, Kozak, Katherine R., Sadowsky, Jack D., Lewis Phillips, Gail D., Guo, Jun, Darwish, Martine, Fan, Peter, Chen, Jingtian, He, Changro

Journal:

ACS Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

30

P1-379: In vivo detection of Alzheimer's disease–linked Aβ peptide accumulation in the lens

Juliet A. Moncaster, Robert D. Moir, Anca G. Mocofanescu, Mark A. Burton, Joy Ghosh, Maria Ericsson, Jack T. Rogers, William E. Klunk, Chester A. Mathis, Martin Sadowski, Thomas Wisniewski, John I. Cl

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 55 KB

english, 2008

31

Relationship between mammographic and histologic features of breast tissue in women with benign biopsies

Roselie A. Bright, Alan S. Morrison, Jacques Brisson, Nelson A. Burstein, Norman S. Sadowsky, Daniel B. Kopans, Jack E. Meyer

Journal:

Year:

1988

Language:

english

File:

PDF, 633 KB

english, 1988

32

High-Resolution Structural Characterization of a Helical α/β-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-xL

Erinna F. Lee, Jack D. Sadowsky, Brian J. Smith, Peter E. Czabotar, Kimberly J. Peterson-Kaufman, Peter M. Colman, Samuel H. Gellman, W. Douglas Fairlie

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 962 KB

english, 2009

33

Breast Imaging

Kopans, Daniel B., Meyer, Jack E., Sadowsky, Norman

Journal:

Boston Medical and Surgical Journal

Year:

1984

File:

PDF, 5.15 MB

1984

34

Coordinated activation of distinct Ca2+ sources and metabotropic glutamate receptors encodes Hebbian synaptic plasticity

Tigaret, Cezar M., Olivo, Valeria, Sadowski, Josef H.L.P., Ashby, Michael C., Mellor, Jack R.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

35

Catalytic cleavage of disulfide bonds in small molecules and linkers of antibody- drug conjugates

Zhang, Donglu, Fourie-O'Donohue, Aimee, Dragovich, Peter S, Pillow, Thomas H, Sadowsky, Jack D, Kozak, Katherine R, Cass, Robert T, Liu, Liling, Deng, Yuzhong, Liu, Yichin, Hop, Cornelis ECA, Khojaste

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 808 KB

english, 2019

36

Ordering a Dynamic Protein Via a Small-Molecule Stabilizer

Wang, Ningkun, Majmudar, Chinmay Y., Pomerantz, William C., Gagnon, Jessica K., Sadowsky, Jack D., Meagher, Jennifer L., Johnson, Taylor K., Stuckey, Jeanne A., Brooks, Charles L., Wells, James A., Ma

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.33 MB

english, 2013

37

Exposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to Tissues

Zhang, Donglu, Dragovich, Peter S., Yu, Shang-Fan, Ma, Yong, Pillow, Thomas H., Sadowsky, Jack D., Su, Dian, Wang, Wei, Polson, Andrew, Khojasteh, S. Cyrus, Hop, Cornelis E.C.A.

Journal:

Drug Metabolism and Disposition

Year:

2019

Language:

english

File:

PDF, 1.15 MB

english, 2019

38

Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies

Nazarova, Lidia, Rafidi, Hanine, Mandikian, Danielle, Ferl, Gregory Z., Koerber, James T., Davies, Christopher W., Ulufatu, Sheila, Ho, Jason, Lau, Jeffrey, Yu, Shang-Fan, Ernst, James, Sadowsky, Jack

Journal:

Molecular Cancer Therapeutics

Year:

2020

File:

PDF, 913 KB

2020

39

Determination of the aqueous-phase structure of 6-O-methylerythromycin from NMR constraints

Wayne E. Steinmetz, Jack D. Sadowsky, Jeffrey S. Rice, John J. Roberts, Yen K. Bui

Journal:

Magnetic Resonance in Chemistry

Year:

2001

Language:

english

File:

PDF, 225 KB

english, 2001

40

Development, optimization and structural characterization of an efficient peptide-based photoaffinity crosslinking reaction for generation of homogeneous conjugates from wild-type antibodies

Sadowsky, Jack, Vance, Nicholas, Zacharias, Neelie, Ultsch, Mark, Li, Guangmin, Fourie, Aimee, Liu, Peter, Lafrance-Vanasse, Julien, Ernst, James Andrew, Sandoval, Wendy, Kozak, Katherine Ruth, Lewis-

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 1020 KB

english, 2018

41

GAL4 Is Regulated by the RNA Polymerase II Holoenzyme–Associated Cyclin-Dependent Protein Kinase SRB10/CDK8

Martin Hirst, Michael S Kobor, Neena Kuriakose, Jack Greenblatt, Ivan Sadowski

Journal:

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

42

Sharp-Wave Ripples Orchestrate the Induction of Synaptic Plasticity during Reactivation of Place Cell Firing Patterns in the Hippocampus

Sadowski, Josef H.L.P., Jones, Matthew W., Mellor, Jack R.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.33 MB

english, 2016

43

On the 1H NMR chemical shift assignments for ampicillin

Janet C. Tung, Angelo J. Gonzales, Jack D. Sadowsky, Daniel J. O’Leary

Journal:

Magnetic Resonance in Chemistry

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

44

ChemInform Abstract: Ring-Closing Metathesis of Olefinic Peptides: Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides.

Helen E. Blackwell, Jack D. Sadowsky, Rebecca J. Howard, Joshua N. Sampson, Jeffery A. Chao, Wayne E. Steinmetz, Daniel J. O'Leary, Robert H. Grubbs

Journal:

Year:

2001

File:

PDF, 25 KB

2001

45

In vivo Detection of Early Alzheimer's Disease-Linked Aβ Peptide Accumulation in the Lens by Non-Invasive Quasi-Elastic Light Scattering

Goldstein, Lee E., Moir, Robert D., Mocofanescu, Anca, Fu, Ling, Lu, Suqian, Burton, Mark A., Xu, Weilan, Ericsson, Maria, Rogers, Jack, Chadwick, Oliver, Sadowski, Martin, Wisniewski, Thomas, Klunk,

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 55 KB

english, 2010

46

Exploration of Structure−Activity Relationships among Foldamer Ligands for a Specific Protein Binding Site via Parallel and Split-and-Mix Library Synthesis

Murray, Justin K., Sadowsky, Jack D., Scalf, Mark, Smith, Lloyd M., Tomita, York, Gellman, Samuel H.

Journal:

Journal of Combinatorial Chemistry

Year:

2008

Language:

english

File:

PDF, 1.62 MB

english, 2008

47

An advanced TALSPEAK concept for separating minor actinides. Part 2. Flowsheet test with actinide-spiked simulant

Wilden, Andreas, Lumetta, Gregg J, Sadowski, Fabian, Schmidt, Holger, Schneider, Dimitri, Gerdes, Markus, Law, Jack D, Geist, Andreas, Bosbach, Dirk, Modolo, Giuseppe

Journal:

Solvent Extraction and Ion Exchange

Year:

2017

Language:

english

File:

PDF, 1.49 MB

english, 2017

48

A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor

Kimberly J. Peterson, Jack D. Sadowsky, Elizabeth A. Scheef, Soumen Pal, Katerina D. Kourentzi, Richard C. Willson, Emery H. Bresnick, Nader Sheibani, Samuel H. Gellman

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 333 KB

english, 2008

49

Comparative Study of a Combination of Isometheptene Mucate, Dichloralphenazone With Acetaminophen and Sumatriptan Succinate in the Treatment of Migraine

Frederick G. Freitag, Roger Cady, Frank DiSerio, Arthur Elkind, R. Michael Gallagher, Jerome Goldstein, Jack A. Klapper, Alan M. Rapoport, Carl Sadowsky, Joel R. Saper, Timothy R. Smith

Journal:

Headache: The Journal of Head and Face Pain

Year:

2001

Language:

english

File:

PDF, 1.13 MB

english, 2001

50

H/D Exchange- and Mass Spectrometry-Based Strategy for the Thermodynamic Analysis of Protein−Ligand Binding

Tang, Liangjie, Hopper, Erin D., Tong, Yan, Sadowsky, Jack D., Peterson, Kimberly J., Gellman, Samuel H., Fitzgerald, Michael C.

Journal:

Analytical Chemistry

Year:

2007

Language:

english

File:

PDF, 158 KB

english, 2007

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